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Recombinant Human ACE2 Protein (His Tag)

  • Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 Protein(C-6His)-Elabscience
  • Recombinant Human ACE2 Protein (His Tag)-Elabscience
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  • Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 Protein(C-6His)-Elabscience
  • Recombinant Human ACE2 Protein (His Tag)-Elabscience
  • Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 Protein(C-6His)-Elabscience
  • Recombinant Human ACE2 Protein (His Tag)-Elabscience
    产品货号:PKSH032068

    别称:Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

    规格:
    • 10μg
    • 50μg
    数量:
    - +
    价格: ¥2624

    Expression_host: Human Cell

    Accession: Q9BYF1

    Overview

    Synonyms Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
    Expression host Human Cell
    Sequence Gln18-Ser740
    Accesstion Q9BYF1
    Species Human
    Mol_Mass 84.6 kDa
    AP_Mol_Mass 103 kDa
    Tag C-6His

    Properties

    Purity > 95 % as determined by reducing SDS-PAGE.
    Endotoxin < 1.0 EU per g as determined by the LAL method.
    Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
    Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
    Formulation Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5.
    Reconstitution Please refer to the printed manual for detailed information.

    Background

    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

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