• 本公司产品仅供体外研究使用,不用于临床诊断

Recombinant Human DPP4/DPPIV/CD26 Protein (Fc Tag)

  • Recombinant Human DPP4 / DPPIV / CD26 Protein (N-Fc)-Elabscience
  • Recombinant Protein-Elabscience
<
>
  • Recombinant Human DPP4 / DPPIV / CD26 Protein (N-Fc)-Elabscience
  • Recombinant Protein-Elabscience
  • Recombinant Human DPP4 / DPPIV / CD26 Protein (N-Fc)-Elabscience
  • Recombinant Protein-Elabscience
    产品货号:PKSH033696

    别称:Dipeptidyl peptidase 4, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26

    规格:
    • 10μg
    • 50μg
    数量:
    - +
    价格: ¥2624

    Expression_host: Human Cell

    Accession: P27487

    Overview

    Synonyms Dipeptidyl peptidase 4, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26
    Expression host Human Cell
    Sequence Asn29-Pro766
    Accesstion P27487
    Species Human
    Mol_Mass 111.7 kDa
    AP_Mol_Mass 105-130 kDa
    Tag N-Fc

    Properties

    Purity > 90% as determined by reducing SDS-PAGE.
    Endotoxin < 1.0 EU per μg as determined by the LAL method.
    Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
    Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
    Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
    Reconstitution Please refer to the printed manual for detailed information.

    Background

    CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. It acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. It may be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, it enhanced cell proliferation, a process inhibited by GPC3. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones.

    Images

    写评论得优惠
    • 全部 (0)
    • 评论 (0)
    • 问答 (0)
    ... 展开 收起

    我的购物车

    产品名称 数量 价格
    结算

    总计:

    诚邀您参与Elabscience生化试剂盒性能验证计划还有积分奖励等你来赢!

    浏览历史


      买了该产品的人还买了