Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-6His)
Price:
Size:
50μg
10μg
- 表达系统: HEK293 Cells
- 蛋白编码: Q9NPH3
别称 |
Interleukin-1 Receptor Accessory Protein;IL-1 Receptor Accessory Protein;IL-1RAcP;Interleukin-1 Receptor 3;IL-1R-3;IL-1R3;IL1RAP;C3orf13;IL1R3
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表达系统 |
HEK293 Cells
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序列 |
Ser21-Glu359
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蛋白编码 |
Q9NPH3
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种属 |
Human
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计算分子量 |
39.9 kDa
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表观分子量 |
50-80 kDa
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标签 |
C-His
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纯度 |
> 95 % as determined by reducing SDS-PAGE.
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内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
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实验操作视频
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