Recombinant Human NCR3/NKp30 Protein (Fc Tag)
Price:
Size:
50μg
10μg
- 表达系统: HEK293 Cells
- 蛋白编码: O14931
别称 |
Natural Cytotoxicity Triggering Receptor 3;Activating Natural Killer Receptor p30;Natural Killer Cell p30-Related Protein;NK-p30;NKp30;CD337;NCR3;1C7;LY117;DAAP-90L16.3;MALS
|
表达系统 |
HEK293 Cells
|
序列 |
Leu19-Thr138
|
蛋白编码 |
O14931
|
种属 |
Human
|
计算分子量 |
40.2 kDa
|
表观分子量 |
50-60 kDa
|
标签 |
C-Fc
|
纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition; NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
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实验操作视频
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