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STAT3 Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB:HepG2,Mouse lung,Mouse lung,Mouse brain,Rat lung,Rat brain
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Stat3
Abbre
STAT3
Synonyms
1110034C02Rik;Acute Phase Response Factor;Acute-phase response factor;ADMIO;APRF;AW109958;DNA binding protein APRF;FLJ20882;HIES;MGC16063;Signal transducer and activator of transcription 3 (acute phase response factor);Signal transducer and activator of transcription 3;STAT 3;Stat3;STAT3抗体
Swissprot
Calculated MW
88kDa
Observed MW
90kDa
Cellular Localization
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.
Concentration
0.97 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Developmental Biology; Signal Transduction; Stem Cells
Conjugation
Unconjugated
Background
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
Western Blot analysis of various samples using STAT3 Polyclonal Antibody at dilution of 1:1000.


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