Vcam1 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB: Mouse spleen, Rat kidney, Rat spleen |
Dilution | WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Rat Vcam1 protein expressed by Mammalian |
Abbre | Vcam1 |
Synonyms | CD106, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1, Vcam-1, Vcam1 |
Swissprot | |
Calculated MW | 81 kDa |
Observed MW | 75-100 kDa |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Conjugation | Unconjugated |
Background | Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation. |
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |