AIF1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Mouse brain,Rat brain |
| Dilution | IHC 1:200-1:800 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to HumanIBA-1 |
| Abbre | AIF1 |
| Synonyms | AIF 1;AIF-1;Aif1;AIF1 protein;AIF1;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Cell projection>ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
| Concentration | 1.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology; Metabolism; Immunology; Neuroscience |
| Conjugation | Unconjugated |
| Background | This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Immunohistochemistry analysis of paraffin-embedded mouse brain using AIF1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using AIF1 Polyclonal Antibody at dilution of 1:300.
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