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AIMP1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human prostate cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human AIMP1
Abbre
AIMP1
Synonyms
AIMP 1;Aimp1;AIMP1/p43;AIMP1;Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1;ARS interacting multifunctional protein 1;EMAP 2;EMAP-2;EMAP-II;EMAP2;EMAPII;Endothelial monocyte activating polypeptide 2;Endothelial monocyte activating polypeptide;Endothelial monocyte-activating polypeptide 2;Endothelial monocyte-activating polypeptide II;HLD3;Multisynthase complex auxiliary component p43;Multisynthetase complex auxiliary component p43;OTTHUMP00000219673;p43;Scye 1;Scye1;Scye1;formerly;Small inducible cytokine subfamily E member 1;Small inducible cytokine subfamily E;member 1 (endothelial monocyte-activating);Small inducible cytokine subfamily E;member 1;formerly抗体
Swissprot
Cellular Localization
Nucleus. Cytoplasm>cytosol. Cytoplasmic vesicle>secretory vesicle. Secreted. Endoplasmic reticulum. Golgi apparatus. Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death.
Concentration
1.56 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Immunology; Tags and Cell Markers
Conjugation
Unconjugated
Background
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using AIMP1 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using AIMP1 Polyclonal Antibody at dilution of 1:55(×200)


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