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APTX Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer,Human cervical cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human APTX
Abbre
APTX
Synonyms
AOA 1;AOA;AOA1;Aprataxin;Aprataxin homolog;Aptx;APTX;Ataxia 1 early onset with hypoalbuminemia;Ataxia1 early onset with hypoalbuminemia;AXA 1;AXA1;EAOH;EOAHA;FHA HIT;FHA-HIT;FLJ20157;Forkhead associated domain histidine triad like;Forkhead associated domain histidine triad like protein;Forkhead-associated domain histidine triad-like protein;MGC1072抗体
Swissprot
Cellular Localization
Nucleus>nucleoplasm. Nucleus>nucleolus. Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage. Colocalizes with MDC1 at sites of DNA double-strand breaks. Interaction with NCL is required for nucleolar localization.
Concentration
0.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using APTX Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using APTX Polyclonal Antibody at dilution 1:50


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