ARIH2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse
- 应用性: WB
Verified Samples |
Verified Samples in WB:Hela,Jurkat,293T,K562,Mouse testis |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human ARIH2 |
Abbre | ARIH2 |
Synonyms | HT005;all trans retinoic acid inducible RING finger;Ari 2;Ari-2;ARI2;ARI2;Ariadne 2;Ariadne 2 protein homolog;ariadne homolog 2 (Drosophila);ariadne homolog 2;Ariadne RBR E3 ubiquitin protein ligase 2;ARIH 2;Arih2;E3 ubiquitin protein ligase ARIH2;E3 ubiquitin-protein ligase ARIH2;protein ariadne 2 homolog;Protein ariadne-2 homolog;Triad 1;TRIAD1;Triad1 protein;UIP48 |
Swissprot | |
Calculated MW | 58kDa |
Cellular Localization | Nucleus. Cytoplasm. |
Concentration | 0.6 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cell Biology; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. |
Western Blot analysis of Hela, Jurkat, 293T and K562 cell, Mouse testis tissue using ARIH2 Polyclonal Antibody at dilution of 1:550
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |