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ARNTL Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB:Human fetal liver,Mouse stomach,Hela,HepG2
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human ARNTL
Abbre
ARNTL
Synonyms
ARNT like protein 1 brain and muscle;Arntl;Aryl hydrocarbon receptor nuclear translocator like;Aryl hydrocarbon receptor nuclear translocator like protein 1;Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic helix loop helix PAS orphan MOP3;Basic helix loop helix PAS protein MOP3;Basic-helix-loop-helix-PAS protein MOP3;bHLH PAS protein JAP3;bHLH-PAS protein JAP3;bHLHe5;BMAL 1;BMAL1;BMAL1c;Brain and muscle ARNT like 1;Brain and muscle ARNT-like 1;CG8727 PA;Class E basic helix-loop-helix protein 5;cycle;JAP 3;JAP3;Member of PAS protein 3;Member of PAS superfamily 3;MGC47515;MOP 3;MOP3;PAS domain-containing protein 3;PASD 3;PASD3;TIC抗体
Swissprot
Calculated MW
69kDa
Cellular Localization
Nucleus. Cytoplasm. Nucleus, PML body. Shuttles between the nucleus and the cytoplasm and this nucleocytoplasmic shuttling is essential for the nuclear accumulation of CLOCK, target gene transcription and the degradation of the CLOCK-ARNTL/BMAL1 heterodimer. The sumoylated form localizes in the PML body. Sequestered to the cytoplasm in the presence of ID2.
Concentration
0.9 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience
Conjugation
Unconjugated
Background
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
Western Blot analysis of Human fetal liver and Mouse stomach tissue, hela and hepG2 cell using ARNTL Polyclonal Antibody at dilution of 1:450
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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