ATP6V1C1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse; Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Human cerebrum,Human cerebella Verified Samples in IHC:Human tonsil |
Dilution | WB 1:500-1:2000;IHC 1:100-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human ATP6V1C1 |
Abbre | ATP6V1C1 |
Synonyms | ATP6C;ATP6D ;ATP6V1C1;ATPase H+ transporting lysosomal (vacuolar proton pump) 42kD;ATPase H+ transporting lysosomal 42kD V1 subunit C isoform 1;ATPase H+ transporting lysosomal 42kDa V1 subunit C isoform 1;ATPase H+ transporting lysosomal 42kDa V1 subunit C1 ;ATPase H+ transporting lysosomal V1 subunit C1;FLJ20057;H(+) transporting two sector ATPase subunit C;H+ ATPase C subunit ;H+ transporting ATPase chain C vacuolar ;Subunit C of vacuolar proton ATPase V1 domain;V ATPase C subunit ;V ATPase subunit C 1;V-ATPase subunit C 1;V-type proton ATPase subunit C 1;Vacuolar ATP synthase subunit C;Vacuolar proton pump 42 kD subunit ;Vacuolar proton pump C subunit ;Vacuolar proton pump subunit C 1;Vacuolar protonATPase subunit C VI domain ;VATC;VATC1;VATPase C subunit ;VATPase subunit C 1;VMA5 |
Swissprot | |
Calculated MW | 44 kDa |
Observed MW | Refer to figures |
Concentration | 0.66 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Metabolism; Signal transduction |
Conjugation | Unconjugated |
Background | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. |
Western blot analysis of Human cerebrum tissue and Human cerebella tissue lysates using ATP6V1C1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human tonsil tissue using ATP6V1C1 Polyclonal Antibody at dilution of 1:100(×200)
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