c-Fos Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主: Mouse
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC-p
Verified Samples |
Verified Samples in WB:Hela,293T,Mouse brain,Rat brain Verified Samples in IHC:Human breast carcinoma |
Dilution | WB 1:500-1:2000;IHC 1:100-1:300 |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Recombinant Protein |
Abbre | c-Fos |
Synonyms | Activator protein 1;AP 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog;FBJ Osteosarcoma Virus;FOS;FOS protein;FOS;G0 G1 switch regulatory protein 7;G0/G1 switch regulatory protein 7;G0S7;Oncogene FOS;p55;proto oncogene c Fos;Proto oncogene protein c fos;Proto-oncogene c-Fos;v fos FBJ murine osteosarcoma viral oncogene homolog |
Swissprot | |
Observed MW | 62kDa |
Cellular Localization | Nucleus. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method | Protein A purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Neuroscience |
Clone No. | 6A3 |
Conjugation | Unconjugated |
Background | Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. |
Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse brain, 4) Rat brain using c-Fos Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using c-Fos Monoclonal Antibody at dilution of 1:200.
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E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
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E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |