CCDC88A Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human cervical cancer,Human colon cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human CCDC88A |
Abbre | CCDC88A |
Synonyms | AKT iphosphorylation enhancer;Akt phosphorylation enhancer;APE;Ccdc88a;Coiled coil domain containing 88A;Coiled coil domain containing protein 88A;Coiled-coil domain-containing protein 88A;FLJ10392;G alpha interacting vesicle associated protein;G alpha-interacting vesicle-associated protein;Galpha interacting vesicle associated protein;Girders of actin filament;Girdin;GIV;GRDN;GRDN;HkRP1;Hook related protein 1;Hook-related protein 1;KIAA1212 |
Swissprot | |
Cellular Localization | Membrane. Cell membrane. Cytoplasm>cytosol. Cytoplasmic vesicle. Cell projection>lamellipodium. Localizes to the cell membrane through interaction with phosphoinositides. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CCDC88A Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using CCDC88A Polyclonal Antibody at dilution 1:50
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |