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CD10 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human brain,Human kidney,Human kidney,Human kidney
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human MME
Abbre
MME
Synonyms
Atriopeptidase;CALLA;CD10;CD10 antigen;Common acute lymphocytic leukemia antigen;DKFZp686O16152;EC 3.4.24.11;Enkephalinase;EPN;Membrane metallo endopeptidase (neutral endopeptidase;enkephalinase);Membrane metallo endopeptidase (neutral endopeptidase;enkephalinase;CALLA;CD10);Membrane metallo endopeptidase;Membrane metallo endopeptidase variant 1;Membrane metallo endopeptidase variant 2;Membrane metalloendopeptidase;Membrane metalloendopeptidase neutral endopeptidase enkephalinase;Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10;Membrane metalloendopeptidase variant 1;Membrane metalloendopeptidase variant 2;MGC126681;MGC126707;MME;NEP;NEP;Neprilysin;neprilysin-390;neprilysin-411;Neutral endopeptidase 24.11;Neutral endopeptidase;Neutral endopeptidase;membrane-associated;SFE;Skin fibroblast elastase抗体
Swissprot
Cellular Localization
Cell membrane.
Concentration
0.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Immunology; Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
Immunohistochemistry of paraffin-embedded Human brain tissue using CD10 Polyclonal Antibody at dilution 1:85


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