CD1A Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： IHC-p;IF
| Verified Samples |
Verified Samples in IHC:Human tonsil Verified Samples in IF:Mouse heart |
| Dilution | IHC 1:100-1:300;IF 1:50-200 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | CD1 |
| Synonyms | CD 1a;CD1;CD1a;CD1A Antigen;CD1A antigen;a polypeptide;CD1a molecule;CD1A;cluster of differentiation 1 A;cortical thymocyte antigen CD1A;differentiation antigen CD1 alpha 3;epidermal dendritic cell marker CD1a;FCB 6;FCB6;HTA 1;HTA1;hTa1 thymocyte antigen;OTTHUMP00000018907;R 4;R4;T 6;T-cell surface antigen T6/Leu-6;T-cell surface glycoprotein CD1a;T6抗体 |
| Swissprot | |
| Cellular Localization | Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. |
| Tissue Specificity | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Immunology |
| Clone No. | Clone:2A5 |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. |
Immunohistochemistry of paraffin-embedded Human tonsil tissue using CD1A Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Mouse heart tissue using CD1A Monoclonal Antibody at dilution of 1:200.
