CD59 Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Human HUVEC,Human U87-MG,Human Hela Verified Samples in IHC:Human ovary |
| Dilution | WB 1:500-1:1000;IHC 1:250-1:500 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human CD59 protein expressed by E.coli |
| Abbre | CD59 |
| Synonyms | 16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD 59;CD_antigen=CD59;CD59;CD59 antigen;CD59 antigen complement regulatory protein ;CD59 antigen p18 20;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5;EJ16;EJ30;EL32 and G344);CD59 glycoprotein;CD59 molecule;CD59 molecule complement regulatory protein;CD59;Cd59a;Complement regulatory protein;EJ16;EJ30;EL32;FLJ38134;FLJ92039;G344;HRF 20;HRF-20;HRF20;Human leukocyte antigen MIC11;Ly 6 like protein;Lymphocytic antigen CD59/MEM43;MAC inhibitory protein;MAC IP;MAC-inhibitory protein;MAC-IP;MACIF;MACIP;MEM43;MEM43 antigen;Membrane attack complex (MAC) inhibition factor;Membrane attack complex inhibition factor;Membrane inhibitor of reactive lysis;MGC2354;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18 20;Protectin;Surface antigen recognized by monoclonal 16.3A5;T cell activating protein |
| Swissprot | |
| Calculated MW | 14kDa |
| Observed MW | 14-17kDa |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Immunology; Signal Transduction; Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. |
Western blot with CD59 Polyclonal antibody at dilution of 1:1000.lane 1:HUVEC whole cell lysate, lane 2:U87-MG whole cell lysate, lane 3:Hela whole cell lysate
Immunohistochemistry of paraffin-embedded Human ovary using CD59 Polyclonal Antibody at dilution of 1:500
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
