CDKL4 Polyclonal Antibody

说明书

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:

200μL 120μL 60μL 20μL

Verified Samples	Verified Samples in WB:Human heart Verified Samples in IHC:Human liver cancer,Human ovarian cancer
Dilution	WB 1:500-1:2000;IHC 1:30-1:150
Clonality	Polyclonal
Isotype	IgG
Immunogen	Synthetic peptide of human CDKL4
Abbre	CDKL4
Synonyms	CDKL4;CDKL4;Cyclin dependent kinase like 4;Cyclin-dependent kinase-like 4;EC 2.7.11.22;OTTHUMP00000164944
Swissprot	Q5MAI5
Calculated MW	43 kDa
Observed MW	Refer to figures
Cellular Localization	Cytoplasm.
Concentration	0.8 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method	Antigen affinity purification
Research Areas	Cell Biology; Signal Transduction
Conjugation	Unconjugated
Background	Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

Western blot analysis of Human heart tissue lysateusing CDKL4 Polyclonal Antibody at dilution of 1:350

Immunohistochemistry of paraffin-embedded Human liver cancer tissueusing CDKL4 Polyclonal Antibody at dilution of 1:35(×200)

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissueusing CDKL4 Polyclonal Antibody at dilution of 1:35(×200)

E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	18mL , 6mL , 3mL
E-IR-R220	Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays