DIABLO Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:LNCaP,SKOV3,MCF-7,293T Verified Samples in IHC:Human colon cancer,Human liver cancer |
| Dilution | WB 1:1000-1:5000;IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human DIABLO |
| Abbre | DIABLO |
| Synonyms | 0610041G12Rik;DBLOH;DBOH;DFNA64;diablo;Diablo homolog (Drosophila);Diablo homolog;Diablo homolog mitochondrial;Diablo IAP binding mitochondrial protein;Diablo like protein;DIABLO S;Direct IAP binding protein with low pI;Direct IAP-binding protein with low pI;FLJ10537;FLJ25049;mitochondrial;Mitochondrial Smac protein;Second mitochondria derived activator of caspase;Second mitochondria-derived activator of caspase;SMAC 3;Smac;Smac protein;SMAC3抗体 |
| Swissprot | |
| Calculated MW | 27kDa |
| Cellular Localization | Mitochondrion. Released into the cytosol when cells undergo apoptosis. |
| Concentration | 0.4 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology; Metabolism |
| Conjugation | Unconjugated |
| Background | This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed. |
Western Blot analysis of Lncap, SKOV3, MCF7 and 293T cell using DIABLO Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human colon cancer using DIABLO Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer using DIABLO Polyclonal Antibody at dilution of 1:50
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
