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DUSP11 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer
Dilution
IHC 1:30-150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Full length fusion protein
Abbre
DUSP11
Synonyms
Dual specificity phosphatase 11;Dual specificity protein phosphatase 11;DUS11;DUSP11;Phosphatase that interacts with RNA/RNP complex 1;PIR1;RNA/RNP complex 1 interacting;RNA/RNP complex interacting phosphatase;RNA/RNP complex-1-interacting phosphatase;RNA/RNP complex1 intereracting phosphatase;Serine/threonine specific protein phosphatase
Swissprot
Cellular Localization
Nucleus.
Concentration
1.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Epigenetics and Nuclear Signaling; Signal transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DUSP11 Polyclonal Antibody at dilution 1:50


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