ELOC Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse; Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human breast cancer,Human ovarian cancer |
Dilution | IHC 1:50-1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human ELOC |
Abbre | ELOC |
Synonyms | Elongin C;Transcription Elongation Factor B (SIII); Polypeptide 1 (15kDa; Elongin C);RNA Polymerase II Transcription Factor SIII Subunit C;Transcription Elongation Factor B Polypeptide 1;Transcription Elongation Factor B Subunit 1;Elongin 15 KDa Subunit;SIII P15.抗体 |
Swissprot | |
Cellular Localization | Cytosol,Nucleus,elongin complex,nucleoplasm |
Concentration | 0.96 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. |
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ELOC Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ELOC Polyclonal Antibody at dilution of 1:55(×200)
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