FDPS Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colorectal cancer,Human esophagus cancer |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human FDPS |
| Abbre | FDPS |
| Synonyms | Dimethylallyltranstransferase;Farnesyl diphosphate synthase;Farnesyl diphosphate synthetase;Farnesyl pyrophosphate synthase;Farnesyl pyrophosphate synthetase;Fdps;FPP synthase;FPP synthetase;FPPS;FPPS_HUMAN;FPS;Geranyltranstransferase |
| Swissprot | |
| Cellular Localization | Cytoplasm |
| Concentration | 1.08 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular;Signal Transduction;Cancer;Metabolism |
| Conjugation | Unconjugated |
| Background | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissueusing FDPS Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissueusing FDPS Polyclonal Antibody at dilution of 1:60(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
