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Fibulin 5 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human lung cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human FBLN5
Abbre
FBLN5
Synonyms
ADCL2;ARCL1A;ARMD3;Dance;Developmental arteries and neural crest EGF like protein;Developmental arteries and neural crest EGF-like protein;EVEC;Fbln5;FBLN5;FIBL 5;FIBL-5;Fibulin-5;FLJ90059;UP50;Urine p50 protein抗体
Swissprot
Cellular Localization
Secreted.
Concentration
1.2 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cardiovascular; Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using Fibulin 5 Polyclonal Antibody at dilution 1:85


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