FUT3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human cervical cancer,Human ovarian cancer |
Dilution | IHC 1:40-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human FUT3 |
Abbre | FUT3 |
Synonyms | Alpha-(1;3/1;4)-fucosyltransferase;Blood group Lewis alpha-4-fucosyltransferase;CD174;FT3B;Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase; Lewis blood group);Fucosyltransferase 3;Fucosyltransferase III;FucT III;FucT-III;FUT3;FUT3;Galactoside 3(4)-L-fucosyltransferase;LE;Les;Lewis FT |
Swissprot | |
Cellular Localization | Golgi apparatus>Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi. |
Concentration | 1.08 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cardiovascular |
Conjugation | Unconjugated |
Background | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. |
Immunohistochemistry of paraffin-embedded Human cervical cancer tissueusing FUT3 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissueusing FUT3 Polyclonal Antibody at dilution of 1:35(×200)
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