GFAP Polyclonal Antibody

货号：E-AB-65069
文献（8）
说明书

说明书

Price: ¥3580.00 ¥2220.00 ¥1380.00

Size:

200 μL 120 μL 60 μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： IHC;IF

Verified Samples	Verified Samples in IHC: Rat brain, Rat cerebellum, Mouse brain Verified Samples in IF: U-251MG, Rat brain, Mouse brain
Dilution	IHC 1:50-1:200, IF 1:50-1:200
Clonality	Polyclonal
Isotype	IgG
Immunogen	A synthetic peptide of human GFAP (NP_002046.1).
Abbre	GFAP
Synonyms	ALXDRD, GFAP
Swissprot	P14136
Cellular Localization	Cytoplasm
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Purification Method	Affinity purification
Research Areas	Cancer, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers
Conjugation	Unconjugated
Background	This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Immunohistochemistry of paraffin-embedded Rat brain using GFAP Polyclonal Antibody at dilution of 1:200 (40x lens).

Immunohistochemistry of paraffin-embedded Rat cerebellum using GFAP Polyclonal Antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded Mouse brain using GFAP Polyclonal Antibody at dilution of 1:100 (40x lens).

Immunofluorescence analysis of U-251MG cells using GFAP Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of Rat brain using GFAP Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of Mouse brain using GFAP Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Alcohol exacerbates psychosocial stress-induced neuropsychiatric symptoms: Attenuation by geraniol

IF: 4.400

Journal： NEUROCHEMISTRY INTERNATIONAL (2024)

DOI：10.1016/j.neuint.2024.105748

Reactivity：Mouse

Sample Type：brains
Protective effect of menthol against thioacetamide-induced hepatic encephalopathy by suppressing oxidative stress and inflammation, augmenting expression of BDNF and α7-nACh receptor, and improving spatial memory

IF: 4.200

Journal： EUROPEAN JOURNAL OF PHARMACOLOGY (2024)

DOI：10.1016/j.ejphar.2024.176916

Reactivity：Rat

Sample Type：hippocampus tissue
Exploring Astrocytes Involvement and Glutamate Induced Neuroinflammation in Chlorpyrifos-Induced Paradigm Of Autism Spectrum Disorders (ASD)

IF: 3.700

Journal： NEUROCHEMICAL RESEARCH (2024)

DOI：10.1007/s11064-024-04191-z

Reactivity：Rat

Sample Type：brain tissue
Synergistic action of vitamin D3 and A on motor activity regulation in mice model of extrapyramidal syndrome: Correlational insights into astrocyte regulation, cytokine modulation, and dopaminergic activity

IF: 2.700

Journal： JOURNAL OF CHEMICAL NEUROANATOMY (2024)

DOI：10.1016/j.jchemneu.2024.102421

Reactivity：Mouse

Sample Type：motor cortex,striatum
Cajanus cajan (L) Millsp seeds extract prevents rotenone-induced motor- and non-motor features of Parkinson disease in mice: Insight into mechanisms of neuroprotection

IF: 5.400

Journal： JOURNAL OF ETHNOPHARMACOLOGY (2023)

DOI：10.1016/j.jep.2023.117623

PMID：38128890

Reactivity：Mouse

Sample Type：brain tissue
Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice

IF: 3.700

Journal： NEUROTOXICITY RESEARCH (2023)

DOI：10.1007/s12640-023-00637-4

PMID：36705862

Reactivity：Mouse

Sample Type：brain
Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement

IF: 3.610

Journal： BRAIN RESEARCH (2022)

DOI：10.1016/j.brainres.2022.147958

PMID：35654119

Reactivity：Mouse

Sample Type：brain
Microglial activation and neurobiological alterations in experimental autoimmune prostatitis-induced depressive-like behavior in mice

IF: 2.989

Journal： Neuropsychiatric Disease and Treatment (2022)

DOI：10.2147/NDT.S211288

PMID：31496706

Reactivity：Mouse

Sample Type：Serum,Tissue

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