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GHR Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB:Raji,K562,SKOV3,PC-3
Dilution
WB 1:500-2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human GHR
Abbre
GHR
Synonyms
GH receptor;GH-binding protein;GHBP;GHBP;included;GHR;GHR;Growth hormone binding protein;Growth hormone receptor;Growth hormone receptor precursor;Growth hormone-binding protein;Growth hormone-binding protein;included;Increased responsiveness to growth hormone;included;Serum binding protein;Serum-binding protein;Somatotropin receptor抗体
Swissprot
Calculated MW
72 kDa
Cellular Localization
Secreted; Cell membrane. On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway and Cell membrane. Remains fixed to the cell membrane and is not internalized.
Concentration
0.3 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell biology; Developmental biology; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.
Western Blot analysis of Raji, K562, skov3 and pc3 cell using GHR Polyclonal Antibody at dilution of 1/400
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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