GHR Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB:Raji,K562,SKOV3,PC-3 |
Dilution | WB 1:500-2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human GHR |
Abbre | GHR |
Synonyms | GH receptor;GH-binding protein;GHBP;GHBP;included;GHR;GHR;Growth hormone binding protein;Growth hormone receptor;Growth hormone receptor precursor;Growth hormone-binding protein;Growth hormone-binding protein;included;Increased responsiveness to growth hormone;included;Serum binding protein;Serum-binding protein;Somatotropin receptor抗体 |
Swissprot | |
Calculated MW | 72 kDa |
Cellular Localization | Secreted; Cell membrane. On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway and Cell membrane. Remains fixed to the cell membrane and is not internalized. |
Concentration | 0.3 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell biology; Developmental biology; Signal transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. |
Western Blot analysis of Raji, K562, skov3 and pc3 cell using GHR Polyclonal Antibody at dilution of 1/400
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |