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GPNMB Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human renal clear cell carcinoma
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human Transmembrane glycoprotein NMB protein
Abbre
GPNMB
Synonyms
Glycoprotein nmb; Glycoprotein nmb like protein; Gpnmb; HGFIN; NMB; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB;
Swissprot
Cellular Localization
Cell membrane, Endosome
Concentration
1mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purification
Research Areas
Immunology; Cancer
Conjugation
Unconjugated
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Immunohistochemistry of paraffin-embedded Human liver cancer using GPNMB Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human renal clear cell carcinoma using GPNMB Polycloanl Antibody at dilution of 1:200.


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