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GRM2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human tonsil
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human GRM2
Abbre
GRM2
Synonyms
AMPA selective glutamate receptor 2 ;GLUR2;GLURB;Glutamate metabotropic receptor 2;Glutamate receptor homolog;Glutamate receptor metabotropic 2;GPRC1B;GRM2;GRM2;Metabotropic glutamate receptor 2;mGlu2;mGluR2;OTTHUMP00000210984;OTTHUMP00000210986抗体
Swissprot
Cellular Localization
Cell membrane.
Concentration
1.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Neuroscience
Conjugation
Unconjugated
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using GRM2 Polyclonal Antibody at dilution of 1:50(×200)


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