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GSR Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Jurkat,Hela,A549
Verified Samples in IHC:Human ovarian cancer
Dilution
WB 1:1000-1:5000;IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human GSR
Abbre
GSR
Synonyms
GLR1;GLUR;Glutathione reductase;Glutathione reductase mitochondrial;Glutathione reductase;mitochondrial;GR;Gr1;GRase;GRD 1;GRD1;GSHR;GSR;MGC78522抗体
Swissprot
Calculated MW
56kDa
Cellular Localization
Cytoplasm and Mitochondrion.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Western Blot analysis of Jurkat, Hela and A549 cell using GSR Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human ovarian cancer using GSR Polyclonal Antibody at dilution of 1:50


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