Histone H2B Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IF
| Verified Samples |
Verified Samples in WB:Hela,3T3,RAW264.7,Rat brain,Rat kidney Verified Samples in IF:Mouse kidney |
| Dilution | WB 1:1000-3000;IF 1:100-200 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | Histone H2B |
| Synonyms | HIST1H2BA;testis;bA317E16.3;H2B;H2B histone family member U;H2B histone family member U testis specific;H2B histone family;member U;(testis specific);H2B testis;H2B1A;H2BFU;H2BT;HIST1H2BA;Histone 1;H2ba;Histone cluster 1 H2ba;Histone H2B;Histone H2B testis;Histone H2B type 1 A;Histone H2B type 1-A;Histone H2B type 1A;STBP;Testis specific histone H2B;Testis-specific histone H2B;TSH 2B;TSH2B;TSH2B.1抗体 |
| Swissprot | |
| Calculated MW | 14kDa |
| Observed MW | 14kDa |
| Cellular Localization | Cytosol,Nucleus,nuclear chromosome, telomeric region,nucleoplasm,nucleus,Other locations:nucleosome |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling |
| Clone No. | Clone:3C3 |
| Conjugation | Unconjugated |
| Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN. |
Western Blot analysis of 1) Hela, 2) 3T3, 3) Raw264.7, 4) Rat brain, 5) Rat kidney using Histone H2B Monoclonal Antibody at dilution of 1:2000.
Immunofluorescence analysis of Mouse kidney tissue using Histone H2B Monoclonal Antibody at dilution of 1:200.
