HLA-DQB2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human HLA-DQB2 |
Abbre | HLA-DQB2 |
Synonyms | DV19.1 (major histocompatibility complex; class II; DQ beta 2 (HLA-DXB));DX-beta;HLA class II histocompatibility antigen; DQ beta 2 chain;HLA class II histocompatibility antigen; DX beta chain;HLA DQB1;HLA DXB;major histocompatibility complex; class II; DQ beta 1;Major histocompatibility complex; class II; DQ beta 2;Major histocompatibility complex; class II; DX beta;MHC class II antigen DQB2 |
Swissprot | |
Cellular Localization | Cell membrane; Single pass type I membrane protein |
Concentration | 1.26 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Immunology |
Conjugation | Unconjugated |
Background | HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissueusing HLA-DQB2 Polyclonal Antibody at dilution of 1:70(×200)
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |