HLA-DRA Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human liver cancer,Human tonsil |
| Dilution | IHC 1:50-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human HLA-DRA |
| Abbre | HLA-DRA |
| Synonyms | DR alpha chain;DR alpha chain precursor;DRA;DRB1;DRB4;Histocompatibility antigen HLA DR alpha;HLA class II histocompatibility antigen;HLA class II histocompatibility antigen DR alpha chain;HLA DR1B;HLA DR3B;HLA DRA;HLA DRA1;HLA DRB1;HLA DRB3;HLA DRB4;HLA DRB5;HLA-DRA;HLADR4B;HLADRA1;HLADRB;Major histocompatibility complex class II DR alpha;Major histocompatibility complex class II DR beta 1;Major histocompatibility complex class II DR beta 3;Major histocompatibility complex class II DR beta 4;Major histocompatibility complex class II DR beta 5;MGC117330;MHC cell surface glycoprotein;MHC class II antigen DRA;MHC II;MLRW抗体 |
| Swissprot | |
| Cellular Localization | Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus>trans-Golgi network membrane. Endosome membrane. Lysosome membrane. Late endosome membrane. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. |
| Concentration | 0.9 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Immunology |
| Conjugation | Unconjugated |
| Background | HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HLA-DRA Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DRA Polyclonal Antibody at dilution of 1:30(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
