IGF1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human kidney cancer,Human lymph nodes cancer |
Dilution | IHC 1:300-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse IGF1 |
Abbre | IGF1 |
Synonyms | IBP1;IGF I;IGF IA;IGF IB;IGF-I;Igf1;IGF1;IGF1A;IGFI;IGFIA;Insulin like growth factor 1 (somatomedin C);Insulin like growth factor 1;Insulin like growth factor IA;Insulin like growth factor IB;Insulin-like growth factor I;Mechano growth factor;MGF;OTTHUMP00000195080;OTTHUMP00000195081;OTTHUMP00000195082;OTTHUMP00000195083;OTTHUMP00000195084;Somatomedia C;Somatomedin C;Somatomedin-C |
Swissprot | |
Cellular Localization | Secreted |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Developmental Biology; Signal Transduction |
Conjugation | Unconjugated |
Background | IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1A. |
Immunohistochemistry analysis of paraffin-embedded human liver cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded human kidney cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded human lymph nodes cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
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