IL37 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human brain |
| Dilution | IHC 1:20-1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human IL37 |
| Abbre | IL37 |
| Synonyms | FIL1;FIL1 zeta;FIL1(ZETA);FIL1Z;IL 1 zeta;IL 1F7;IL 1F7b (IL 1H4;IL 1H;IL 1RP1);IL 1H4;IL 1RP1;IL 1X;IL 1X protein;IL-1 zeta;IL-1F7;IL-1H;IL-1H4;IL-1RP1;IL-1X;IL-37;IL1F7 (canonical product IL 1F7b);IL1F7;IL1F7;IL1H4;IL1RP1;Interleukin 1 family member 7;interleukin 1 family;member 7 (zeta);Interleukin 1 homolog 4;Interleukin 1 related protein;Interleukin 1 superfamily z;Interleukin 1 zeta;Interleukin 37;Interleukin-1 family member 7;Interleukin-1 homolog 4;Interleukin-1 zeta;Interleukin-1-related protein;Interleukin-23抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation. |
| Concentration | 1.44 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Immunology |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G. |
Immunohistochemistry of paraffin-embedded Human brain tissue using IL37 Polyclonal Antibody at dilution of 1:50(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
