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IL4R Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human tonsil
Dilution
IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human IL4R
Abbre
IL4R
Synonyms
CD124;IL 4R alpha;IL-4 receptor subunit alpha;IL-4-binding protein;IL-4R subunit alpha;IL-4R-alpha;IL-4RA;IL4-BP;Il4r;IL4R nirs variant 1;IL4RA;IL4RA;Interleukin 4 receptor alpha chain;Interleukin 4 receptor;sIL4Ralpha/prot;Soluble IL-4 receptor subunit alpha;Soluble IL-4R-alpha;Soluble interleukin-4 receptor subunit alpha抗体
Swissprot
Cellular Localization
Secreted and Cell membrane.
Concentration
1.26 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Immunology
Conjugation
Unconjugated
Background
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL4R Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL4R Polyclonal Antibody at dilution of 1:45(×200)


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