IL4R Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human tonsil |
Dilution | IHC 1:30-1:150 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human IL4R |
Abbre | IL4R |
Synonyms | CD124;IL 4R alpha;IL-4 receptor subunit alpha;IL-4-binding protein;IL-4R subunit alpha;IL-4R-alpha;IL-4RA;IL4-BP;Il4r;IL4R nirs variant 1;IL4RA;IL4RA;Interleukin 4 receptor alpha chain;Interleukin 4 receptor;sIL4Ralpha/prot;Soluble IL-4 receptor subunit alpha;Soluble IL-4R-alpha;Soluble interleukin-4 receptor subunit alpha抗体 |
Swissprot | |
Cellular Localization | Secreted and Cell membrane. |
Concentration | 1.26 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Immunology |
Conjugation | Unconjugated |
Background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL4R Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL4R Polyclonal Antibody at dilution of 1:45(×200)
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |