KCNN2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse; Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer |
Dilution | IHC 1:30-1:150 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human KCNN2 |
Abbre | KCNN2 |
Synonyms | Apamin sensitive small conductance Ca2+ activated potassium;Apamin sensitive small conductance Ca2+ activated potassium channel;hSK2;KCa2.2;Kcnn2;Potassium intermediate/small conductance calcium activated;Potassium intermediate/small conductance calcium activated channel subfamily N member 2;SK2;SKCa 2;SKCa2;Small conductance calcium activated potassium channel;Small conductance calcium activated potassium channel protein 2;Small conductance calcium-activated potassium channel protein 2抗体 |
Swissprot | |
Cellular Localization | Plasma Membrane,Other locations:cell surface,dendritic spine,integral component of membrane,neuronal cell body,Z disc |
Concentration | 0.78 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Neuroscience |
Conjugation | Unconjugated |
Background | Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants.
KCNN2 (Potassium Calcium-Activated Channel Subfamily N Member 2) is a Protein Coding gene. Among its related pathways are Serotonergic synapse and Bile secretion. GO annotations related to this gene include protein homodimerization activity and ion channel activity. An important paralog of this gene is KCNN3. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using KCNN2 Polyclonal Antibody at dilution of 1:30(×200)
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |