LEP Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colon,Human stomach,Mouse liver,Rat lung |
| Dilution | IHC 1:100 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Leptin |
| Abbre | LEP |
| Synonyms | FLJ94114;LEP;LEP;LEPD;Leptin (murine obesity homolog);Leptin (obesity homolog;mouse);Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese protein;Obese;mouse;homolog of;Obesity;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285抗体 |
| Swissprot | |
| Cellular Localization | Adipose tissue is the main source of leptin it is also produced by other peripheral tissues such as the skeletal muscle (PubMed:7789654, PubMed:16052473, PubMed:12448771). Expressed by intercalated and striated tracts of submandibular and parotid salivary gland intralobular ducts (PubMed:12448771). Detected by fundic epithelium of the gastric mucosa (PubMed:10896907). Secreted into blood and gastric juice (PubMed:10896907). |
| Concentration | 210 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. |
Immunohistochemistry analysis of paraffin-embedded human colon using LEP Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded human stomach using LEP Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded mouse liver using LEP Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded Rat lung using LEP Polyclonal Antibody at dilution of 1:100.
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| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
