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MCM3 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:K562,Jurkat,Hela,293T
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human MCM3
Abbre
MCM3
Synonyms
Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;DNA polymerase alpha holoenzyme associated protein P1;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor mcm3;HCC 5;HCC5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM 3;mcm3;MCM3 minichromosome maintenance deficient 3;MCM3;MGC1157;Minichromosome maintenance complex component 3;Minichromosome maintenance deficient 3;Minichromosome maintenance protein 3;P1 h;P1 MCM3;P1 Protein;P1-MCM3;P1.h;p102;P102 protein;Replication licensing factor beta subunit;RLF beta subunit;RLF subunit beta;RLFB抗体
Swissprot
Calculated MW
91kDa
Cellular Localization
Nucleus.
Concentration
0.3 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Western Blot analysis of K562, Jurkat, hela and 293T cell using MCM3 Polyclonal Antibody at dilution of 1:550
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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