MCM3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse
- 应用性: WB
Verified Samples |
Verified Samples in WB:K562,Jurkat,Hela,293T |
Dilution | WB 1:500-1:2000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human MCM3 |
Abbre | MCM3 |
Synonyms | Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;DNA polymerase alpha holoenzyme associated protein P1;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor mcm3;HCC 5;HCC5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM 3;mcm3;MCM3 minichromosome maintenance deficient 3;MCM3;MGC1157;Minichromosome maintenance complex component 3;Minichromosome maintenance deficient 3;Minichromosome maintenance protein 3;P1 h;P1 MCM3;P1 Protein;P1-MCM3;P1.h;p102;P102 protein;Replication licensing factor beta subunit;RLF beta subunit;RLF subunit beta;RLFB抗体 |
Swissprot | |
Calculated MW | 91kDa |
Cellular Localization | Nucleus. |
Concentration | 0.3 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. |
Western Blot analysis of K562, Jurkat, hela and 293T cell using MCM3 Polyclonal Antibody at dilution of 1:550
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |