MutS Protein Homolog 2(MSH2) Monoclonal Antibody
Price:
Size:
200μL
100μL
6mL
3mL
- 宿主: Mouse
- 反应性: Human
- 应用性: IHC-P
Verified Samples |
Verified Samples in IHC:Human colon cancer tissue |
Size |
3mL/6mL(即用型);100μL/200μL(浓缩型) |
Clonality | Monoclonal |
Abbre | MutS Protein Homolog 2(MSH2) |
Synonyms | MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2 |
Swissprot | |
Cellular Localization | Nucleus |
Storage | The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months. |
Research Areas | Cancer;Epigenetics and Nuclear Signaling |
Clone No. | YN01126m |
Conjugation | Unconjugated |
Background | DNA错配修复(MMR)系统是指由特异修复DNA碱基错配的酶分子组成。这套系统的存在,可保证遗传物质的完整性和稳定性,避免遗传物质的突变产生,保证DNA复制的高度保真。它由hMLH1,hMSH2,hPMS1,hPMS2等基因组成,hMSH2位于人类染色体2p21-22,编码是一种由934氨基酸组成的蛋白质,hMSH2基因突变发生在散发性结直肠癌中,微卫星hMSH2基因突变大约与50%的家族性,非家族性息肉病发生的结直肠癌(HNPCC)相关。 |
福尔马林固定,石蜡包埋,EDTA修复,人体结肠癌组织MSH2染色。
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |