MutS Protein Homolog 6(MSH6) Monoclonal Antibody
Price:
Size:
200μL
100μL
6mL
3mL
- 宿主: Mouse
- 反应性: Human
- 应用性: IHC-P
Verified Samples |
Verified Samples in IHC:Human colon cancer tissue |
Size |
3mL/6mL(即用型);100μL/200μL(浓缩型) |
Clonality | Monoclonal |
Abbre | MutS Protein Homolog 6(MSH6) |
Synonyms | MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2 |
Swissprot | |
Cellular Localization | Nucleus |
Storage | The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months. |
Research Areas | Cancer;Epigenetics and Nuclear Signaling |
Clone No. | YN01136m |
Conjugation | Unconjugated |
Background | MSH6全称为MutS homolog 6,(E.coli),是一种错配修复基因,定位在2号染色体的P臂的16位上。DNA错配修复对于超时遗传信息完整性的维持是非常必要的。微卫星的重现性的改变是由于DNA复制时铰链不对位产生滑动而导致的结果,又称为微卫星不稳定性。突变型的错配修复蛋白常表达于高频度微卫星不稳定(MSI-H)患者中,与常染色体的显性遗传相关,也称为遗传性非息肉病性结、直肠癌 (HNPCC),也可见于散发性(MSI-H)结、直肠癌患者。MLH1、MSH2、MSH6抗体可用于患者及其家族对该疾病的筛查。文献报道高频度微卫星不稳(MSI-L)及微卫星稳定(MSS)的患者的预后好。 |
福尔马林固定,石蜡包埋,EDTA修复,人体结肠癌组织MSH6染色。
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |