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MYOZ2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Full length fusion protein
Abbre
MYOZ2
Synonyms
C4orf5;Calcineurin binding protein calsarcin 1;Calsarcin 1;Calsarcin-1;Calsarcin1;CMH16;CS 1;CS1;FATZ related protein 2;FATZ-related protein 2;Muscle specific protein;MYOZ 2;MYOZ2;MYOZ2;Myozenin-2;Myozenin2
Swissprot
Cellular Localization
Cytoplasm>myofibril>sarcomere>Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Concentration
1.32 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cardiovascular; Signal Transduction
Conjugation
Unconjugated
Background
MYOZ2 (Myozenin 2) is a Protein Coding gene. Diseases associated with MYOZ2 include Cardiomyopathy, Hypertrophic, 16 and Myoz2-Related Familial Hypertrophic Cardiomyopathy. GO annotations related to this gene include actin binding and telethonin binding. An important paralog of this gene is MYOZ1.The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
Immunohistochemistry of paraffin-embedded Human liver cancer tissueusing MYOZ2 Polyclonal Antibody at dilution of 1:40(×200)


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