NAE1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Human fetal muscle,Human kidney,Human liver |
| Dilution | WB 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human NAE1 |
| Abbre | NAE1 |
| Synonyms | 59 kDa;A 116A10.1;Amyloid beta precursor protein binding protein 1 59kD;Amyloid beta precursor protein binding protein 1 59kDa;Amyloid beta precursor protein binding protein 1;Amyloid beta precursor protein binding protein 1;59 kDa;Amyloid beta precursor protein-binding protein 1;Amyloid protein binding protein 1;Amyloid protein-binding protein 1;APP BP1;APP-BP1;APPBP 1;APPBP1;HPP 1;HPP1;NAE 1;NAE1;NEDD8 activating enzyme E1 regulatory subunit;NEDD8 activating enzyme E1 subunit 1;NEDD8 activating enzyme E1 subunit;NEDD8-activating enzyme E1 regulatory subunit;Proto oncogene protein 1;Proto-oncogene protein 1;Protooncogene protein 1;ula 1;ULA1 |
| Swissprot | |
| Calculated MW | 60kDa |
| Cellular Localization | Cell membrane. Colocalizes with APP in lipid rafts. |
| Concentration | 0.1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
Western Blot analysis of Human fetal muscle, kidney and liver tissue using NAE1 Polyclonal Antibody at dilution of 1:500
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
