PARP1 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human
- 应用性： WB
| Verified Samples |
Verified Samples in WB:Hela,293T,Jurkat |
| Dilution | WB 1:1000-3000 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic Peptide |
| Abbre | PARP |
| Synonyms | ADP-ribosyltransferase diphtheria toxin-like 1;ADPRT 1;ADPRT;ADPRT1;APOPAIN;ARTD1;NAD(+) ADP-ribosyltransferase 1;PARP;PARP-1;PARP1;PARP1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;Poly[ADP-ribose] synthase 1;PPOL;SCA1抗体 |
| Swissprot | |
| Observed MW | 116kDa |
| Cellular Localization | Nucleus. Nucleus, nucleolus. Localizes at sites of DNA damage. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism |
| Clone No. | Clone:1L5 |
| Conjugation | Unconjugated |
| Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
Western Blot analysis of 1) Hela, 2) 293T, 3) Jurkat cells using PARP1 Monoclonal Antibody at dilution of 1:2000.
| E-AB-1001 | Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1024 | Goat Anti-Mouse IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1196 | HRP-Goat Anti-Mouse IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
