Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody

Verified Samples in WB:Mouse lung,Mouse liver,Rat kidney,HepG2,HepG2,3T3,3T3
Verified Samples in IHC:Human colon
Verified Samples in IF:Mouse liver

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:50-1:200

Polyclonal

IgG

Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182

p38 (phospho Thr180/Tyr182)

CSAID Binding Protein 1;CSAID binding protein;CSAID-binding protein;Csaids binding protein;CSBP 1;CSBP 2;CSBP;CSBP1;CSBP2;CSPB1;Cytokine suppressive anti-inflammatory drug-binding protein;EXIP;MAP kinase 14;MAP kinase MXI2;MAP kinase p38 alpha;MAPK 14;MAPK14;MAX interacting protein 2;MAX-interacting protein 2;Mitogen Activated Protein Kinase 14;Mitogen activated protein kinase p38 alpha;Mitogen-activated protein kinase 14;Mitogen-activated protein kinase p38 alpha;MK14;Mxi 2;MXI2;p38 ALPHA;p38;p38 MAP kinase;p38 MAPK;p38 mitogen activated protein kinase;p38ALPHA;p38alpha Exip;PRKM14;PRKM15;RK;SAPK2A抗体

41kDa

38kDa

Cytoplasm. Nucleus.

Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Immunology; Signal Transduction

Unconjugated

MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.