Phospho-SMAD2/3 (Thr8) Polyclonal Antibody

Verified Samples in WB:VEC

WB 1:500-1:2000

Polyclonal

IgG

Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8

Smad2/3 (phospho Thr8)

SMAD2;MADH2;MADR2;Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;SMAD3;MADH3;Mothers against decapentaplegic抗体

48kDa

48kDa

Cytosol,Nucleus,heteromeric SMAD protein complex,nuclear chromatin,nuclear inner membrane,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,receptor complex,SMAD protein complex,transcription factor complex

SMAD2 is Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Epigenetics and Nuclear Signaling; Signal Transduction; Stem Cells

Unconjugated

SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.