PPARD Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： IHC-p;IF
| Verified Samples |
Verified Samples in IHC:Human uterus Verified Samples in IF:Mouse spleen |
| Dilution | IHC 1:100-200;IF 1:100-200 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein of PPAR Delta of PPAR Delta |
| Abbre | PPAR Delta Mouse (2F9) |
| Synonyms | FAAR;MGC3931;NR1C2;NUC1;NUCI;NUCII;Nuclear hormone receptor 1;Nuclear receptor subfamily 1 group C member 2;Peroxisome proliferative activated receptor delta;Peroxisome proliferator-activated receptor beta (PPAR-beta);Peroxisome proliferator-activated receptor beta;Peroxisome proliferator-activated receptor delta;PPAR beta;PPAR-beta;PPAR-delta;PPAR-;PPARB;ppard;PPARD抗体 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Tissue Specificity | Ubiquitous with maximal levels in placenta and skeletal muscle. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism |
| Clone No. | Clone:5F4 |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. |
Immunohistochemistry of paraffin-embedded Human uterus tissue using PPARD Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Mouse spleen tissue using PPARD Monoclonal Antibody at dilution of 1:200.
