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PPM1M Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human tonsil
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human PPM1M
Abbre
PPM1M
Synonyms
FLJ32332;PP2C eta;PP2C-eta;PP2CE;PP2Ceta;PPM1M;PPM1M;protein phosphatase 1M (PP2C domain containing);Protein phosphatase 1M;Protein phosphatase 2C isoform eta抗体
Swissprot
Cellular Localization
Nucleus.
Concentration
1.74 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal transduction
Conjugation
Unconjugated
Background
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200)


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