PPY Polyclonal Antibody(Capture/Detector)
Price:
Size:
100μg
50μg
- 宿主： Rabbit
- 反应性： Human
- 应用性： ELISA(Cap/Det):2-8 mg/mL(Cap);0.1-0.4 mg/mL(Det) ln a sandwich ELISA, this antibody can be used as capture or detector antibody when paired with(Catalog # D-AB-10160F)or (Catalog # D-AB-10160P).
| Dilution | 2-8mg/ml(Cap);0.1-0.4mg/ml(Det) |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant Human PPY Protein expressed by E.coli |
| Abbre | PPY |
| Synonyms | Pancreatic polypeptide prohormone;PH;Pancreatic polypeptide Y;Pancreatic polypeptide;Pancreatic icosapeptide;PPY;PNP |
| Swissprot | |
| Concentration | 1mg/mL |
| Storage | Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Purification Method | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Background | Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying. |
Sandwich ELISA-Recombinant Human PPY protein standard curve.Background subtracted standard curve using Anti-PPY antibody(D-AB-10160F/P)(Capture),Anti-PPY antibody(D-AB-10160F/P)(Detector).The reference range value is 62.5-4000 pg/ml for Human.
| D-AB-10160P | PPY Polyclonal Antibody(Capture/Detector) | 500μg |
