PYCARD Polyclonal Antibody

货号：E-AB-30582
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说明书

说明书

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:

200μL 120μL 60μL 20μL

宿主： Rabbit
反应性： Human;Mouse;Rat
应用性： WB;IHC-p;IF

Verified Samples	Verified Samples in WB:K562,Hela,3T3,293 Verified Samples in IHC:Human stomach cancer
Dilution	WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
Clonality	Polyclonal
Isotype	IgG
Immunogen	Synthesized peptide derived from the N-terminal region of human ASC
Abbre	ASC
Synonyms	Apoptosis associated speck like protein containing a CARD;Apoptosis-associated speck-like protein containing a CARD;ASC;ASC;CARD 5;CARD5;Caspase recruitment domain containing protein 5;Caspase recruitment domain protein 5;Caspase recruitment domain-containing protein 5;hASC;MGC10332;PYCARD;PYD and CARD domain containing;PYD and CARD domain containing protein;PYD and CARD domain-containing protein;Target of methylation induced silencing 1;Target of methylation-induced silencing 1;TMS 1;TMS;TMS1抗体
Swissprot	Q9ULZ3
Calculated MW	22kDa
Observed MW	21kDa
Cellular Localization	Cytoplasm. Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures.
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Research Areas	Cancer; Cell Biology
Conjugation	Unconjugated
Background	Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Western Blot analysis of various cells using PYCARD Polyclonal Antibody at dilution of 1:1000.

Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PYCARD Polyclonal Antibody at dilution of 1:200.

Effect of alcohol on chronic pelvic pain and prostatic inflammation in a mouse model of experimental autoimmune prostatitis

IF: 2.876

Journal：PROSTATE

DOI：10.1002/pros.23866

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