Recombinant Human AGR2 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： O95994
| 别称 |
Anterior Gradient Protein 2 Homolog;AG-2;hAG-2;HPC8;Secreted Cement Gland Protein XAG-2 Homolog;AGR2;AG2
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| 表达系统 |
HEK293 Cells
|
| 序列 |
Arg21-Leu175
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| 蛋白编码 |
O95994
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| 种属 |
Human
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| 计算分子量 |
18.9 kDa
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| 表观分子量 |
18 kDa
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| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 10%Glycerol, 0.01%Tween80, pH8.0.
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| 复溶方法 |
Not Applicable
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| 背景 |
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
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实验操作视频
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